Paper 1 1. Discuss factors affecting drug distribution and the significance of plasma protein binding.
2. Angiotensin converting enzyme inhibitors (ACEIs): mechanism of action, therapeutic uses and
3. Propranolol: pharmacokinetics properties, therapeutic uses and adverse effects.
4. Parkinsonism: drugs used in treatment, possible combinations and adverse effects.
5. Classify anti-asthmatic drugs with examples. Discuss pharmacokinetics of theophylline.
6. Discuss in short the mechanism of action of anti microbial that act on bacterial protein
7. Benzodiazebines: mechanism of action, members and indications.
8. Thionamides (thiouracils) mechanism of action, members and indications.
9. Compare between uses of H2-receptors antagonists and proton pump inhibitors.
10. Anti-platelet drugs: discuss the mechanisms of action of six drugs.
Paper II: 1. Define tolerance and its possible causes.
2. Adverse effects may follow sudden withdrawal of some drugs: give examples.
3. Define non-compliance and its causes.
4. What is meant by teratogenicity, give examples.
5. Enumerate drugs used in treatment of hypercalcemia.
6. Mention five adverse effects of glucocorticoids.
7. Mention drugs used in treatment of infertility.
8. Adverse effects of oral contraceptive pills.
9. Mention four therapeutic uses of neuro-muscular blocker.
10. Adverse effects of sodium valproate.
11. Mention the most suitable local anaesthetic used for surface anaesthesia and explain why.
12. Fluoxentine: mechanism of action and advantages.
13. Praziquantel: mechanism of action and indications.
14. Adverse effects of Methotrexate.
15. Indications of acyclovir.
16. advantages of f