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تاريخ التسجيل : 27/06/2009

مُساهمةموضوع: امتحانmcqرقم(3)   الثلاثاء سبتمبر 22, 2009 5:54 pm

MBBS SECOND PROFESSIONAL EXAMINATION 2007
PHARMACOLOGY AND THERAPEUTICS (MCQs)
MODEL PAPER


26. Glyceryl trinitrate relieves stable (atherosclerotic) angina by:
a. Producing cGMP-dependent vasodilatation
b. Reducing preload of the heart
c. Reducing afterload on the heart
d. Causing redistribution of blood in coronaries
e. All of the above
Key: e


Table of Specification: MCQ No. 27 –29.

27. A diuretic that can lead to alkalinization of urine is:
a. Acetazolamide
b. Bendrofluazide
c. Frusemide
d. Amiloride
e. Ammonium chloride
Key: a


28. A diuretic that produces its action mainly by acting on the
proximal part of distal convoluted tubules is:
a. Ethacrynic acid
b. Triamterene
c. Hydroxychlorothiazide
d. Spironolactone
e. Mannitol
Key: c


29. A diuretic that acts by inhibiting Na/K/2Cl symport in the renal
tubules is :
a. Bendrofluazide
b. Frusemide
c. Amiloride
d. Acetazolamide
e. Spironolactone
Key: b


Table of Specification: MCQ No. 30 – 32.

30. Warfarin:
a. Is generally administered by intramuscular injection
b. Has a quick onset of action
c. Inactivates factor XIIa
d. Is antagonized by Vitamin K-1
e. Activated partial thromboplastin time is used to regulate its dosage
Key: d



Page 7 of 13
MBBS SECOND PROFESSIONAL EXAMINATION 2007
PHARMACOLOGY AND THERAPEUTICS (MCQs)
MODEL PAPER

31. A drug that inhibits ADP -induced platelet aggregation is:
a. Abciximab
b. Aspirin
c. Eptifibatide
d. Clopidorel
e. Tirofiban
Key: d


32. A drug suitable for treatment of familial hypretriglyceridemia :
a. Gemfibrozil
b. Simvastatin
c. Colestipol
d. Cholestyramine
e. Atorvastatin
Key: a


Table of Specification: MCQ No. 33 –36.

33. While traveling by car to a hill-station, a child suffered from
nausea and vomiting. In order to prevent these symptoms to
occur during return journey you would prescribe:
a. Atropine
b. Promethazine
c. Ondensatron
d. Diphenoxylate
e. Chlorpromazine
Key: b


34. Acid rebound phenomenon is likely to occur with the use of:
a. Magnesium trisilicate
b. Aluminum hydroxide
c. Sodium bicarbonate
d. Aluminum phosphate
e. Sucralfate
Key: c


35. A drug that causes purgation by local irritation of small intestine
is:
a. Senna
b. Bisacodyl
c. Sorbitol
d. Castor oil
e. Aloes
Key: d



Page 8 of 13
MBBS SECOND PROFESSIONAL EXAMINATION 2007
PHARMACOLOGY AND THERAPEUTICS (MCQs)
MODEL PAPER

36. Loperamide and Diphenoxylate :
a. Are very effective in controlling the diarrhoea of severe ulcerative
colitis.
b. Are preferred for control of diarrhoeas caused by infections
c. Are primarily used in treatment of diarrhoeas in infants
d. Should be preferred over ORS therapy in childhood diarrhoeas
e. May produce substantial improvement in diarrhoea of irritable bowel
syndrome
Key: e


Table of Specification: MCQ No. 37 – 40.

37. The following drug will produce bronchodilatation in an
asthmatic patient:
a. Ipratropium
b. Montelukast
c. Beclomethasone
d. Nedochromil
e. Cromolyn Sodium
Key: a


38. Theophylline is helpful in bronchial asthma by:
a. Inhibiting phosphodiesterase
b. Blocking Adenosine receptors
c. Reversing fatigue of diaphragm
d. Inhibiting antigen-induced release of histamine
e. All of the above
Key: e


39. A patient presenting with acute episode of bronchial asthma
should be preferably treated with:
a. Oral administration of LTD-4 receptor blockers
b. Administration of Mast Cell Stabilizing drugs by aerosol
c. Administration of long acting Beta-2 receptor agonists by inhalation
d. Administration of short acting Beta-2 receptor agonists by inhalation
e. Oral administration of slow-release tablets of theophylline
Key: d


40. An opium-alkaloid solely used as a cough suppressant is:
a. Codeine
b. Thebaine
c. Noscapine
d. Papaverine
e. Dextromethorphan
Key: c




Page 9 of 13
MBBS SECOND PROFESSIONAL EXAMINATION 2007
PHARMACOLOGY AND THERAPEUTICS (MCQs)
MODEL PAPER

Table of Specification: MCQ No. 41 – 46.

41. A drug that acts by inhibiting bacterial topoisomerase is:
a. Co-trimoxazole
b. Doxycycline
c. Ofloxacin
d. Amikacin
e. Clindamycin
Key: c


42. Which of the following cephalosporins is more likely to be
associated with hypoprothrombinemia :
a. Ceftriaxone
b. Cefoperazone
c. Ceftazidime
d. Ceftizoxime
e. Cefaclor
Key: b


43. Which of the following drugs may be used in regimens for
eradication of H. pylori?
a. Clarithromycin
b. Tobramycin
c. Ticarcillin
d. Ciprofloxacin
e. Albendazole
Key: a


44. Sulphamethoxazole is combined with trimethoprim in co-
trimoxazole because the two drugs:
a. Have matching volumes of distribution
b. Have similar plasma protein binding
c. Have matching half lives
d. Inhibit different metabolic pathways in the organisms
e. Are excreted through the same route
Key: c


45. The aminoglycosides are not effective against anaerobic bacteria
because :
a. These organisms do not have binding sites for aminoglycosides
b. These drugs fail to enter into anaerobes
c. These drugs are actively effluxed from anaerobes
d. These drugs are inactivated under anaerobic conditions
e. The anaerobes produce inactivating enzymes against
aminoglycosides
Key: b



Page 10 of 13
MBBS SECOND PROFESSIONAL EXAMINATION 2007
PHARMACOLOGY AND THERAPEUTICS (MCQs)
MODEL PAPER

46. The tetracyclines are not prescribed to the growing children
because they:
a. May cause pseudomembranous enterocolitis
b. May cause photosensitivity
c. May cause severe vertigo
d. May impair bony growth
e. May cause Fanconi -like syndrome
Key: d


Table of Specification: MCQ No. 47 –49.

47. In the chemotherapy of tuberculosis:
a. Ethambutol is the most quickly acting sterilizer.
b. Pyrazinamide is active at neutral pH
c. Streptomycin acts better against intracellular bacilli
d. Rifabutin causes more drug interactions than rifampin
e. Neurotoxicity of isoniazid is reversed by pyridoxine
Key: e


48. Which of the following antimalarial drugs will eradicate the
relapses in a patient of benign tertian malaria?
a. Primaquine
b. Mefloquine
c. Artemether
d. Pyremethamine
e. Sulfadoxine
Key: a


49. The drug of choice for treatment of T aenia saginata infestation is :
a. Mebendazole
b. Pyrantel pamoate
c. Albendazole
d. Praziquantel
e. Ivermectin
Key: d


Table of Specification: MCQ No. 50 – 51.

50. Which one of the following antiviral agents is used against
infections caused by cytomegalovirus?
a. Ganciclovir
b. Amantadine
c. Adefovir
d. Ribavarin
e. Idoxuridine
Key: a
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